实际上，许多医疗数据集在疾病标签空间上定义了基本的分类学。但是，现有的医学诊断分类算法通常假定具有语义独立的标签。在这项研究中，我们旨在利用深度学习算法来利用类层次结构，以更准确，可靠的皮肤病变识别。我们提出了一个双曲线网络，以共同学习图像嵌入和类原型。事实证明，双曲线为与欧几里得几何形状更好地建模层次关系提供了一个空间。同时，我们使用从类层次结构编码的距离矩阵限制双曲线原型的分布。因此，学习的原型保留了嵌入空间中的语义类关系，我们可以通过将图像特征分配给最近的双曲线类原型来预测图像的标签。我们使用内部皮肤病变数据集，该数据集由65种皮肤疾病的大约230k皮肤镜图像组成，以验证我们的方法。广泛的实验提供了证据表明，与模型相比，我们的模型可以实现更高的准确性，而在不考虑班级关系的情况下可以实现更高的严重分类错误。

近年来，自动化方法迅速发展了皮肤病变和分类的方法。由于此类系统在诊所中的部署越来越多，因此很重要的是，为各种分布（OOD）样品（未知的皮肤病变和状况）开发更强大的系统。但是，当前对皮肤病变分类训练的深度学习模型倾向于将这些OOD样品错误地分类为他们学习的皮肤病变类别之一。为了解决这个问题，我们提出了一种简单而战略的方法，可以改善OOD检测性能，同时维持已知皮肤病变类别的多类分类精度。要说明，这种方法建立在皮肤病变图像的长尾且细粒度检测任务的现实情况之上。通过这种方法，1）首先，我们针对中间和尾巴之间的混合，以解决长尾问题。 2）后来，我们将上述混合策略与原型学习结合在一起，以解决数据集的细粒度。本文的独特贡献是两倍，这是通过广泛的实验证明的。首先，我们提出了针对皮肤病变的OOD任务的现实问题。其次，我们提出了一种针对问题设置的长尾且细粒度方面的方法，以提高OOD性能。

The success of neural networks builds to a large extent on their ability to create internal knowledge representations from real-world high-dimensional data, such as images, sound, or text. Approaches to extract and present these representations, in order to explain the neural network's decisions, is an active and multifaceted research field. To gain a deeper understanding of a central aspect of this field, we have performed a targeted review focusing on research that aims to associate internal representations with human understandable concepts. In doing this, we added a perspective on the existing research by using primarily deductive nomological explanations as a proposed taxonomy. We find this taxonomy and theories of causality, useful for understanding what can be expected, and not expected, from neural network explanations. The analysis additionally uncovers an ambiguity in the reviewed literature related to the goal of model explainability; is it understanding the ML model or, is it actionable explanations useful in the deployment domain?

Many problems in machine learning involve bilevel optimization (BLO), including hyperparameter optimization, meta-learning, and dataset distillation. Bilevel problems consist of two nested sub-problems, called the outer and inner problems, respectively. In practice, often at least one of these sub-problems is overparameterized. In this case, there are many ways to choose among optima that achieve equivalent objective values. Inspired by recent studies of the implicit bias induced by optimization algorithms in single-level optimization, we investigate the implicit bias of gradient-based algorithms for bilevel optimization. We delineate two standard BLO methods -- cold-start and warm-start -- and show that the converged solution or long-run behavior depends to a large degree on these and other algorithmic choices, such as the hypergradient approximation. We also show that the inner solutions obtained by warm-start BLO can encode a surprising amount of information about the outer objective, even when the outer parameters are low-dimensional. We believe that implicit bias deserves as central a role in the study of bilevel optimization as it has attained in the study of single-level neural net optimization.

An expansion of aberrant brain cells is referred to as a brain tumor. The brain's architecture is extremely intricate, with several regions controlling various nervous system processes. Any portion of the brain or skull can develop a brain tumor, including the brain's protective coating, the base of the skull, the brainstem, the sinuses, the nasal cavity, and many other places. Over the past ten years, numerous developments in the field of computer-aided brain tumor diagnosis have been made. Recently, instance segmentation has attracted a lot of interest in numerous computer vision applications. It seeks to assign various IDs to various scene objects, even if they are members of the same class. Typically, a two-stage pipeline is used to perform instance segmentation. This study shows brain cancer segmentation using YOLOv5. Yolo takes dataset as picture format and corresponding text file. You Only Look Once (YOLO) is a viral and widely used algorithm. YOLO is famous for its object recognition properties. You Only Look Once (YOLO) is a popular algorithm that has gone viral. YOLO is well known for its ability to identify objects. YOLO V2, V3, V4, and V5 are some of the YOLO latest versions that experts have published in recent years. Early brain tumor detection is one of the most important jobs that neurologists and radiologists have. However, it can be difficult and error-prone to manually identify and segment brain tumors from Magnetic Resonance Imaging (MRI) data. For making an early diagnosis of the condition, an automated brain tumor detection system is necessary. The model of the research paper has three classes. They are respectively Meningioma, Pituitary, Glioma. The results show that, our model achieves competitive accuracy, in terms of runtime usage of M2 10 core GPU.

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge typically rely on automated evaluations on limited benchmarks. There is no standard to evaluate model predictions and reasoning across a breadth of tasks. To address this, we present MultiMedQA, a benchmark combining six existing open question answering datasets spanning professional medical exams, research, and consumer queries; and HealthSearchQA, a new free-response dataset of medical questions searched online. We propose a framework for human evaluation of model answers along multiple axes including factuality, precision, possible harm, and bias. In addition, we evaluate PaLM (a 540-billion parameter LLM) and its instruction-tuned variant, Flan-PaLM, on MultiMedQA. Using a combination of prompting strategies, Flan-PaLM achieves state-of-the-art accuracy on every MultiMedQA multiple-choice dataset (MedQA, MedMCQA, PubMedQA, MMLU clinical topics), including 67.6% accuracy on MedQA (US Medical License Exam questions), surpassing prior state-of-the-art by over 17%. However, human evaluation reveals key gaps in Flan-PaLM responses. To resolve this we introduce instruction prompt tuning, a parameter-efficient approach for aligning LLMs to new domains using a few exemplars. The resulting model, Med-PaLM, performs encouragingly, but remains inferior to clinicians. We show that comprehension, recall of knowledge, and medical reasoning improve with model scale and instruction prompt tuning, suggesting the potential utility of LLMs in medicine. Our human evaluations reveal important limitations of today's models, reinforcing the importance of both evaluation frameworks and method development in creating safe, helpful LLM models for clinical applications.

Migraine is a high-prevalence and disabling neurological disorder. However, information migraine management in real-world settings could be limited to traditional health information sources. In this paper, we (i) verify that there is substantial migraine-related chatter available on social media (Twitter and Reddit), self-reported by migraine sufferers; (ii) develop a platform-independent text classification system for automatically detecting self-reported migraine-related posts, and (iii) conduct analyses of the self-reported posts to assess the utility of social media for studying this problem. We manually annotated 5750 Twitter posts and 302 Reddit posts. Our system achieved an F1 score of 0.90 on Twitter and 0.93 on Reddit. Analysis of information posted by our 'migraine cohort' revealed the presence of a plethora of relevant information about migraine therapies and patient sentiments associated with them. Our study forms the foundation for conducting an in-depth analysis of migraine-related information using social media data.

Human linguistic capacity is often characterized by compositionality and the generalization it enables -- human learners can produce and comprehend novel complex expressions by composing known parts. Several benchmarks exploit distributional control across training and test to gauge compositional generalization, where certain lexical items only occur in limited contexts during training. While recent work using these benchmarks suggests that pretrained models achieve impressive generalization performance, we argue that exposure to pretraining data may break the aforementioned distributional control. Using the COGS benchmark of Kim and Linzen (2020), we test two modified evaluation setups that control for this issue: (1) substituting context-controlled lexical items with novel character sequences, and (2) substituting them with special tokens represented by novel embeddings. We find that both of these setups lead to lower generalization performance in T5 (Raffel et al., 2020), suggesting that previously reported results have been overestimated due to uncontrolled lexical exposure during pretraining. The performance degradation is more extreme with novel embeddings, and the degradation increases with the amount of pretraining data, highlighting an interesting case of inverse scaling.

Machine learning model development and optimisation can be a rather cumbersome and resource-intensive process. Custom models are often more difficult to build and deploy, and they require infrastructure and expertise which are often costly to acquire and maintain. Machine learning product development lifecycle must take into account the need to navigate the difficulties of developing and deploying machine learning models. evoML is an AI-powered tool that provides automated functionalities in machine learning model development, optimisation, and model code optimisation. Core functionalities of evoML include data cleaning, exploratory analysis, feature analysis and generation, model optimisation, model evaluation, model code optimisation, and model deployment. Additionally, a key feature of evoML is that it embeds code and model optimisation into the model development process, and includes multi-objective optimisation capabilities.

Despite recent progress towards scaling up multimodal vision-language models, these models are still known to struggle on compositional generalization benchmarks such as Winoground. We find that a critical component lacking from current vision-language models is relation-level alignment: the ability to match directional semantic relations in text (e.g., "mug in grass") with spatial relationships in the image (e.g., the position of the mug relative to the grass). To tackle this problem, we show that relation alignment can be enforced by encouraging the directed language attention from 'mug' to 'grass' (capturing the semantic relation 'in') to match the directed visual attention from the mug to the grass. Tokens and their corresponding objects are softly identified using the cross-modal attention. We prove that this notion of soft relation alignment is equivalent to enforcing congruence between vision and language attention matrices under a 'change of basis' provided by the cross-modal attention matrix. Intuitively, our approach projects visual attention into the language attention space to calculate its divergence from the actual language attention, and vice versa. We apply our Cross-modal Attention Congruence Regularization (CACR) loss to UNITER and improve on the state-of-the-art approach to Winoground.